C5′ Methylene Proton Signal Assignment of DNA/RNA Oligomers Labeled with C5′-Monodeuterated Nucleosides by1H-31P HSQC Spectroscopy

1996 ◽  
Vol 34 (13) ◽  
pp. S40-S46 ◽  
Author(s):  
Akira Ono ◽  
Takako Makita ◽  
Shin-ichi Tate ◽  
Etsuko Kawashima ◽  
Yoshiharu Ishido ◽  
...  
Keyword(s):  
Methylene Proton ◽  
Signal Assignment ◽  
Proton Signal ◽  
Rna Oligomers ◽  
Methylene Proton Signal

1H NMR Study of Polyisoprenes

1980 ◽  
Vol 53 (2) ◽  
pp. 305-312 ◽  
Author(s):  
H. Sato ◽  
Y. Tanaka
Keyword(s):  
1H Nmr ◽  
Nmr Spectra ◽  
Methine Proton ◽  
Broad Peak ◽  
Methylene Proton ◽  
Methyl Proton ◽  
Nmr Study ◽  
In Cis ◽  
Methylene Proton Signal

Abstract 1H NMR spectra of polyisoprene were assigned using polymers of isoprene-1,1,4,4-d4, isoprene-1,1,5,5,5-d5, and isoprene-4,4-d2 polymerized with various catalysts. The methylene-proton signal at 2.1 ppm in cis-1,4- and trans-1,4-polyisoprenes was divided into H4- and H1-proton signals; H4 resonated at 2.21 ppm in both cis-1,4 and trans-1,4 units, whereas H1 resonated at 2.05, 2.21, and 2.15 ppm. Splitting due to the dyad sequences of 1,4 and 3,4 units was apparent. The methine-proton (H3) in a 3,4 unit showed a broad peak centered around 1.5 ppm in C6D6. The overlapping of this signal with the methyl-proton signals at 1.73 and 1.63 ppm resulted in some uncertainty in the determination of the microstructure of polyisoprene which contained a considerable amount of 3,4 unit.

scholarly journals Harnessing Chemical Energy for the Activation and Joining of Prebiotic Building Blocks

2019 ◽  
Author(s):  
Ziwei Liu ◽  
Long-Fei Wu ◽  
Jianfeng Xu ◽  
Claudia Bonfio ◽  
David Russell ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Carboxylic Acid ◽  
Peptide Nucleic Acid ◽  
Reactive Intermediates ◽  
Building Blocks ◽  
Acid System ◽  
Rna Oligomers ◽  
Prebiotic Activation ◽  
Simultaneous Activation ◽  
Acid Anhydrides

Simultaneous activation of carboxylates and phosphates provides multiple pathways for the generation of reactive intermediates, including mixed carboxylic acid-phosphoric acid anhydrides, for the synthesis of peptidyl-RNAs, peptides, RNA oligomers and primordial phospholipids. These results indicate that unified prebiotic activation chemistry could have enabled the joining of building blocks in aqueous solution from a common pool and enabled the progression of a system towards higher complexity foreshadowing the modern encapsulated peptide-nucleic acid system

A graphene oxide coated tapered microfiber acting as a super-sensor for rapid detection of SARS-CoV-2

Lab on a Chip ◽  
2021 ◽  
Author(s):  
Hao Jia ◽  
Ao Zhang ◽  
Yuquan Yang ◽  
Yaqi Cui ◽  
Jianrong Xu ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Rapid Detection ◽  
Innovative Approach ◽  
Sensor System ◽  
System P ◽  
Rna Oligomers ◽  
Optical Microfiber

COVID-19 is a new strain of highly contagious coronavirus. Now, an innovative approach to detect it by combining DNA/RNA oligomers as aptamers and a GO coated optical microfiber as a sensor system.

Zur Reaktivität von C=N-Doppelbindungssystemen, VIII PMR-spektroskopische Untersuchungen zur E/Z-Isomerie von α-Nitrozimtsäureestern.

1976 ◽  
Vol 31 (5) ◽  
pp. 594-598 ◽  
Author(s):  
Otto S. Wolfbeis
Keyword(s):  
Acetic Anhydride ◽  
Shift Reagent ◽  
Simple Method ◽  
Signal Assignment ◽  
E And Z Isomers

The preparation of the title compounds from aldehyd-aniles and alkylnitroacetates in acetic anhydride is described. The nitrocinnamates, which in solution are mixtures of the E- and Z-isomers, are studied PMR-spectroscopically, using Eu(fod)3 as a shift reagent. A simple method for the signal assignment is worked out, making it unnecessary to prepare pure diastereomers.

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